GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs2243480 | 1 | rs4718317 | chr7:65648901 | CRCP | chr7:65579805-65619551:+ | 0.3 | 4.66 | 4.1E-6 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718317 | chr7:65648901 | LOC493754 | chr7:65993446-66057363:- | -0.29 | -3.43 | 0.000654 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718317 | chr7:65648901 | RABGEF1 | chr7:66093890-66276446:+ | -0.55 | -6.87 | 1.95E-11 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718333 | chr7:65772758 | CCT6P1 | chr7:65216092-65228661:+ | -0.42 | -6.62 | 9.41E-11 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718333 | chr7:65772758 | CRCP | chr7:65579805-65619551:+ | 0.28 | 4.19 | 3.25E-5 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718333 | chr7:65772758 | LOC493754 | chr7:65993446-66057363:- | -0.29 | -3.34 | 0.000897 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718333 | chr7:65772758 | RABGEF1 | chr7:66093890-66276446:+ | -0.6 | -7.29 | 1.25E-12 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718334 | chr7:65789454 | CCT6P1 | chr7:65216092-65228661:+ | -0.42 | -6.56 | 1.43E-10 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718334 | chr7:65789454 | CRCP | chr7:65579805-65619551:+ | 0.27 | 4.07 | 5.4E-5 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718334 | chr7:65789454 | LOC493754 | chr7:65993446-66057363:- | -0.3 | -3.39 | 0.000744 | Diabetic kidney disease |
| THCA | cis | rs2243480 | 1 | rs4718334 | chr7:65789454 | RABGEF1 | chr7:66093890-66276446:+ | -0.6 | -7.42 | 5.44E-13 | Diabetic kidney disease |
| THCA | cis | rs875971 | 1 | rs4718343 | chr7:65874288 | ASL | chr7:65540776-65558321:+ | -0.16 | -4.16 | 3.75E-5 | Aortic root size |
| THCA | cis | rs875971 | 1 | rs4718343 | chr7:65874288 | GUSB | chr7:65425675-65447246:- | 0.27 | 5.34 | 1.43E-7 | Aortic root size |
| THCA | cis | rs875971 | 1 | rs4718343 | chr7:65874288 | RABGEF1 | chr7:66093890-66276446:+ | 0.65 | 14.09 | 5.98E-38 | Aortic root size |
| THCA | cis | rs875971 | 1 | rs4718344 | chr7:65874381 | ASL | chr7:65540776-65558321:+ | -0.16 | -4.27 | 2.36E-5 | Aortic root size |